Verfügbarkeit: Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L.

Gespeichert in:

Bibliographische Detailangaben
Titel:	Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L.
Von:	vorgelegt von Josef Maximilian Herrmann
Person:	Herrmann, Josef Maximilian 1983- Verfasser aut
Hauptverfasser:	Herrmann, Josef Maximilian 1983- (VerfasserIn)
Format:	Abschlussarbeit Buch
Sprache:	Englisch
Veröffentlicht:	2013
Schlagworte:	Naturstoff Mäusedorn Chemische Synthese Alkohole Desoxygenierung Hochschulschrift
Online-Zugang:	http://epub.uni-regensburg.de/28806/ https://nbn-resolving.org/urn:nbn:de:bvb:355-epub-288069 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027485022&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
Beschreibung:	145 S. Ill., graph. Darst.

Internformat

MARC


LEADER	00000nam a2200000 c 4500
001	BV042043810
003	DE-604
005	20150109
007	t\|
008	140826s2013 xx ad\|\| m\|\|\| 00\|\|\| eng d
035			\|a (OCoLC)890027013
035			\|a (DE-599)BVBBV042043810
040			\|a DE-604 \|b ger \|e rakwb
041	0		\|a eng
049			\|a DE-384 \|a DE-473 \|a DE-703 \|a DE-1051 \|a DE-824 \|a DE-29 \|a DE-12 \|a DE-91 \|a DE-19 \|a DE-1049 \|a DE-92 \|a DE-739 \|a DE-898 \|a DE-355 \|a DE-706 \|a DE-20 \|a DE-1102
082	0		\|a 540
084			\|a VK 5075 \|0 (DE-625)147396: \|2 rvk
100	1		\|a Herrmann, Josef Maximilian \|d 1983- \|e Verfasser \|0 (DE-588)1056945559 \|4 aut
245	1	0	\|a Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L. \|c vorgelegt von Josef Maximilian Herrmann
264		1	\|c 2013
300			\|a 145 S. \|b Ill., graph. Darst.
336			\|b txt \|2 rdacontent
337			\|b n \|2 rdamedia
338			\|b nc \|2 rdacarrier
502			\|a Regensburg, Univ., Diss., 2013
650	0	7	\|a Naturstoff \|0 (DE-588)4041418-8 \|2 gnd \|9 rswk-swf
650	0	7	\|a Mäusedorn \|0 (DE-588)7518729-2 \|2 gnd \|9 rswk-swf
650	0	7	\|a Chemische Synthese \|0 (DE-588)4133806-6 \|2 gnd \|9 rswk-swf
650	0	7	\|a Alkohole \|0 (DE-588)4141899-2 \|2 gnd \|9 rswk-swf
650	0	7	\|a Desoxygenierung \|0 (DE-588)4149192-0 \|2 gnd \|9 rswk-swf
655		7	\|0 (DE-588)4113937-9 \|a Hochschulschrift \|2 gnd-content
689	0	0	\|a Mäusedorn \|0 (DE-588)7518729-2 \|D s
689	0	1	\|a Naturstoff \|0 (DE-588)4041418-8 \|D s
689	0	2	\|a Chemische Synthese \|0 (DE-588)4133806-6 \|D s
689	0		\|5 DE-604
689	1	0	\|a Alkohole \|0 (DE-588)4141899-2 \|D s
689	1	1	\|a Desoxygenierung \|0 (DE-588)4149192-0 \|D s
689	1		\|5 DE-604
776	0	8	\|i Erscheint auch als \|n Online-Ausgabe \|o urn:nbn:de:bvb:355-epub-288069
856	4	1	\|u http://epub.uni-regensburg.de/28806/ \|x Verlag \|z kostenfrei \|3 Volltext
856	4		\|u https://nbn-resolving.org/urn:nbn:de:bvb:355-epub-288069 \|x Resolving-System
856	4	2	\|m DNB Datenaustausch \|q application/pdf \|u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027485022&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA \|3 Inhaltsverzeichnis
912			\|a ebook
943	1		\|a oai:aleph.bib-bvb.de:BVB01-027485022

Datensatz im Suchindex

DE-BY-OTHR_katkey	5481295
DE-BY-TUM_katkey	2022685
DE-BY-UBR_call_number	230/VK 5075 H568 86/VK 5075 H568
DE-BY-UBR_katkey	5481295
DE-BY-UBR_location	UB Magazin UB Lesesaal Chemie / Pharmazie
DE-BY-UBR_media_number	069038298213 069039937093
_version_	1835078386181996544
adam_text	TABLE OF CONTENTS 1 REDUCTIVE DEOXYGENATION OF ALCOHOLS - CATALYTIC METHODS BEYOND BARTON MCCOMBIE DEOXYGENATION 3 1.1 INTRODUCTION 3 1.2 DEOXYGENATIONS EMPLOYING A TWO-STEP PROCEDURE 5 1.2.1 DEOXYGENATION OF ALCOHOL DERIVATIVES (ETHERS, ESTERS) 5 1.2.2 DEOXYGENATION OF ALCOHOLS VIA ELIMINATION-HYDROGENATION SEQUENCE 1S 1.3 DIRECT REDUCTIVE DEOXYGENATION OF ALCOHOLS 18 1.3.1 DIRECT DEOXYGENATION WITH HYDROGENATION CATALYSTS 18 1.3.2 (LEWIS) ACID CATALYZED DIRECT DEOXYGENATIONS 21 1.4 CONCLUSION 26 1.5 REFERENCES 27 2 REDUCTION OF BENZYLIC ALCOHOLS AND A-HYDROXYCARBONYL COMPOUNDS BY HYDRIODIC ACID IN A BIPHASIC REACTION MEDIUM 33 2.1 INTRODUCTION 33 2.2 RESULTS AND DISCUSSION 34 2.2.1 DEOXYGENATION OF BENZYLIC ALCOHOLS 34 2.2.2 DEOXYGENATION OF ALLYLIC AND PROPARGYLIC ALCOHOLS 36 2.2.3 CONVERSION OF ALIPHATIC ALCOHOLS WITHOUT JI-SYSTEM IN A-POSITION 37 2.2.4 MECHANISM OF THE DEOXYGENATION WITH HYDRIODIC ACID 38 2.2.5 DEOXYGENATION WITH CATALYTIC AMOUNTS OF HYDRIODIC ACID 39 2.3 CONCLUSIONS 41 2.4 EXPERIMENTAL 42 2.5 REFERENCES 46 HTTP://D-NB.INFO/1058713574 3 SYNTHESIS OF NOVEL NATURAL PRODUCTS ISOLATED FROM BUTCHERS BROOM 51 3.1 BENZOXEPINES ISOLATED FROM BUTCHERS BROOM 51 3.2 SYNTHESIS OF THE RUSCOZEPINES AND ANALOGOUS BENZOXEPINES 53 3.2.1 RUSCOZEPINE A, B AND ANALOGOUS BENZOXEPINES 55 3.2.2 SYNTHESIS OF 8-METHOXY-2,3-DIHYDROBENZO[B]OXEPIN-7-OL 65 3.2.3 NITROGEN ANALOG OF RUSCOZEPINES - BENZAZEPINE 66 3.3 PHARMACOLOGY 67 3.3.1 RHIZOMA EXTRACT OF RUSCUS ACULEATUS L 67 3.3.2 MTT VIABILITY ASSAY - CYTOTOXICITY 67 3.3.3 ICAM-1 EXPRESSION INHIBITION ASSAY - ANTI-INFLAMMATORY ACTIVITY 68 3.3.4 ORAC-FLUORESCEIN ASSAY - ANTIOXIDANT ACTIVITY 70 3.4 CONCLUSION 72 3.5 EXPERIMENTAL 73 3.5.1 PREPARATION OF COMPOUNDS 73 3.5.2 PHARMACOLOGICAL TESTING 107 3.6 REFERENCES 109 4 SUMMARY ILL 5 ZUSAMMENFASSUNG 112 6 APPENDIX 115 6.1 ABBREVIATIONS 115 6.2 COPIES OF SELECTED NMR - SPECTRA 118 6.3 LIST OF PRESENTATIONS AND PUBLICATIONS 141 6.4 CURRICULUM VITAE 142 6.5 DANKSAGUNGEN 144
any_adam_object	1
author	Herrmann, Josef Maximilian 1983-
author_GND	(DE-588)1056945559
author_facet	Herrmann, Josef Maximilian 1983-
author_role	aut
author_sort	Herrmann, Josef Maximilian 1983-
author_variant	j m h jm jmh
building	Verbundindex
bvnumber	BV042043810
classification_rvk	VK 5075
collection	ebook
ctrlnum	(OCoLC)890027013 (DE-599)BVBBV042043810
dewey-full	540
dewey-hundreds	500 - Natural sciences and mathematics
dewey-ones	540 - Chemistry and allied sciences
dewey-raw	540
dewey-search	540
dewey-sort	3540
dewey-tens	540 - Chemistry and allied sciences
discipline	Chemie / Pharmazie
format	Thesis Book
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02221nam a2200493 c 4500</leader><controlfield tag="001">BV042043810</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20150109 </controlfield><controlfield tag="007">t\|</controlfield><controlfield tag="008">140826s2013 xx ad\|\| m\|\|\| 00\|\|\| eng d</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)890027013</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV042043810</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-384</subfield><subfield code="a">DE-473</subfield><subfield code="a">DE-703</subfield><subfield code="a">DE-1051</subfield><subfield code="a">DE-824</subfield><subfield code="a">DE-29</subfield><subfield code="a">DE-12</subfield><subfield code="a">DE-91</subfield><subfield code="a">DE-19</subfield><subfield code="a">DE-1049</subfield><subfield code="a">DE-92</subfield><subfield code="a">DE-739</subfield><subfield code="a">DE-898</subfield><subfield code="a">DE-355</subfield><subfield code="a">DE-706</subfield><subfield code="a">DE-20</subfield><subfield code="a">DE-1102</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">540</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">VK 5075</subfield><subfield code="0">(DE-625)147396:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Herrmann, Josef Maximilian</subfield><subfield code="d">1983-</subfield><subfield code="e">Verfasser</subfield><subfield code="0">(DE-588)1056945559</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L.</subfield><subfield code="c">vorgelegt von Josef Maximilian Herrmann</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2013</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">145 S.</subfield><subfield code="b">Ill., graph. Darst.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="502" ind1=" " ind2=" "><subfield code="a">Regensburg, Univ., Diss., 2013</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Naturstoff</subfield><subfield code="0">(DE-588)4041418-8</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Mäusedorn</subfield><subfield code="0">(DE-588)7518729-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Chemische Synthese</subfield><subfield code="0">(DE-588)4133806-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Alkohole</subfield><subfield code="0">(DE-588)4141899-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Desoxygenierung</subfield><subfield code="0">(DE-588)4149192-0</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="0">(DE-588)4113937-9</subfield><subfield code="a">Hochschulschrift</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Mäusedorn</subfield><subfield code="0">(DE-588)7518729-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Naturstoff</subfield><subfield code="0">(DE-588)4041418-8</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="2"><subfield code="a">Chemische Synthese</subfield><subfield code="0">(DE-588)4133806-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="1" ind2="0"><subfield code="a">Alkohole</subfield><subfield code="0">(DE-588)4141899-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="1"><subfield code="a">Desoxygenierung</subfield><subfield code="0">(DE-588)4149192-0</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Online-Ausgabe</subfield><subfield code="o">urn:nbn:de:bvb:355-epub-288069</subfield></datafield><datafield tag="856" ind1="4" ind2="1"><subfield code="u">http://epub.uni-regensburg.de/28806/</subfield><subfield code="x">Verlag</subfield><subfield code="z">kostenfrei</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="856" ind1="4" ind2=" "><subfield code="u">https://nbn-resolving.org/urn:nbn:de:bvb:355-epub-288069</subfield><subfield code="x">Resolving-System</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">DNB Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027485022&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ebook</subfield></datafield><datafield tag="943" ind1="1" ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-027485022</subfield></datafield></record></collection>
genre	(DE-588)4113937-9 Hochschulschrift gnd-content
genre_facet	Hochschulschrift
id	DE-604.BV042043810
illustrated	Illustrated
indexdate	2024-12-20T17:00:48Z
institution	BVB
language	English
oai_aleph_id	oai:aleph.bib-bvb.de:BVB01-027485022
oclc_num	890027013
open_access_boolean	1
owner	DE-384 DE-473 DE-BY-UBG DE-703 DE-1051 DE-824 DE-29 DE-12 DE-91 DE-BY-TUM DE-19 DE-BY-UBM DE-1049 DE-92 DE-739 DE-898 DE-BY-UBR DE-355 DE-BY-UBR DE-706 DE-20 DE-1102
owner_facet	DE-384 DE-473 DE-BY-UBG DE-703 DE-1051 DE-824 DE-29 DE-12 DE-91 DE-BY-TUM DE-19 DE-BY-UBM DE-1049 DE-92 DE-739 DE-898 DE-BY-UBR DE-355 DE-BY-UBR DE-706 DE-20 DE-1102
physical	145 S. Ill., graph. Darst.
psigel	ebook
publishDate	2013
publishDateSearch	2013
publishDateSort	2013
record_format	marc
spellingShingle	Herrmann, Josef Maximilian 1983- Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L. Naturstoff (DE-588)4041418-8 gnd Mäusedorn (DE-588)7518729-2 gnd Chemische Synthese (DE-588)4133806-6 gnd Alkohole (DE-588)4141899-2 gnd Desoxygenierung (DE-588)4149192-0 gnd
subject_GND	(DE-588)4041418-8 (DE-588)7518729-2 (DE-588)4133806-6 (DE-588)4141899-2 (DE-588)4149192-0 (DE-588)4113937-9
title	Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L.
title_auth	Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L.
title_exact_search	Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L.
title_full	Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L. vorgelegt von Josef Maximilian Herrmann
title_fullStr	Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L. vorgelegt von Josef Maximilian Herrmann
title_full_unstemmed	Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L. vorgelegt von Josef Maximilian Herrmann
title_short	Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L.
title_sort	reductive deoxygenation of alcohols synthesis of novel natural products isolated from ruscus aculeatus l
topic	Naturstoff (DE-588)4041418-8 gnd Mäusedorn (DE-588)7518729-2 gnd Chemische Synthese (DE-588)4133806-6 gnd Alkohole (DE-588)4141899-2 gnd Desoxygenierung (DE-588)4149192-0 gnd
topic_facet	Naturstoff Mäusedorn Chemische Synthese Alkohole Desoxygenierung Hochschulschrift
url	http://epub.uni-regensburg.de/28806/ https://nbn-resolving.org/urn:nbn:de:bvb:355-epub-288069 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027485022&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
work_keys_str_mv	AT herrmannjosefmaximilian reductivedeoxygenationofalcoholssynthesisofnovelnaturalproductsisolatedfromruscusaculeatusl

Verfügbarkeit

Per Ortsleihe bestellen

Volltext (frei zugänglich)