Gespeichert in:
| Titel: | Reward prediction errors in the brain methodological, developmental and psychiatric aspects of (mal-)adaptive learning and decision making |
|---|---|
| Von: |
by Tobias U. Hauser
|
| Person: |
Hauser, Tobias U.
1984- Verfasser aut |
| Hauptverfasser: | |
| Format: | Abschlussarbeit Buch |
| Sprache: | Englisch Deutsch |
| Veröffentlicht: |
Zurich
2013
|
| Schlagworte: | |
| Online-Zugang: | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027390821&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| Beschreibung: | Zsfassung in dt. Sprache |
| Beschreibung: | 163, 2 S. Ill., graph. Darst. |
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Datensatz im Suchindex
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| adam_text | Titel: Reward prediction errors in the brain
Autor: Hauser, Tobias U
Jahr: 2013
Contents
Summary 5
Zusammenfassung 9
1 General Introduction 13
1.1 Adaptive learning and decision making - from algorithms
to neural networks............................................13
1.2 (Mai-) adaptive learning and decision making - from de-
velopment to psychiatry......................................15
1.2.1 Decision making during Adolescence................16
1.2.2 Decision making in ADHD ..........................16
1.3 Methods to study (mal-)adaptive learning and decision
making - simultaneous EEG-fMRI..........................19
1.4 General aims and hypotheses................................22
2 Study A 24
2.1 Abstract.....................................25
2.2 Introduction....................................................26
2.3 Material and methods........................................30
2.3.1 Subjects................................................30
2.3.2 Task....................................................30
2.3.3 Reinforcement learning model........................32
2.3.4 EEG acquisition......................................34
2.3.5 EEG analyses..........................................34
2.3.6 fMRI acquisition......................................36
2.3.7 fMRI analyses ........................................436
2.3.8 Effective connectivity analysis using dynamic causal
modeling (DCM)......................................38
2.4 Results..........................................................39
2.4.1 Reinforcement learning model............39
2.4.2 Localization of the FRN..............................40
2.4.3 The influence of RPEs on the FRN amplitude ... 40
2.4.4 Effective connectivity of the FRN source......42
2.5 Discussion......................................................43
2.6 Conclusions....................................................30
2.7 Acknowledgements............................................50
2.8 Conflict of interest............................................51
2.9 Supplementary materials......................................51
2.9.1 Supplementary analyses: The relation between sR-
PEs, |RPEs| and the FRNGA ........................51
3 Study B 57
3.1 Abstract........................................................58
3.2 Introduction....................................................58
3.3 Materials and methods........................................61
3.3.1 Participants............................................61
3.3.2 Task....................................................61
3.3.3 Reinforcement learning models...........63
3.3.4 Model estimation and comparison .........65
3.3.5 Data acquisition......................................66
3.3.6 fMRI data analysis....................................66
3.4 Results..........................................................68
3.4.1 Behavior..............................68
3.4.2 Model comparison....................................68
3.4.3 Model parameters...................69
3.4.4 fMRI analysis..........................................72
3.5 Discussion..........................................73
3.6 Acknowledgments....................... 78
3.7 Conflict of interest...................... 78
3.8 Supplementary materials................... 78
4 Study C 79
4.1 Abstract............................ 80
4.2 Introduction.......................... 80
4.3 Results............................. 83
4.3.1 Behavioral model comparison............ 84
4.3.2 Model parameter comparison............ 86
4.3.3 Neural correlates of RPE processing........ 87
4.3.4 Neural group differences in RPE processing .... 88
4.3.5 Analysis of the sgACC/VS-ROI........... 90
4.3.6 Neural correlates of the decision steepness..... 91
4.3.7 Temporal aspects of RPE processing: Feedback-
related negativity (FRN) .............. 91
4.3.8 Localization of the FRN............... 93
4.4 Discussion........................... 93
4.5 Experimental Procedures .................. 98
4.5.1 Participants...................... 98
4.5.2 Task.......................... 98
4.5.3 Behavioral Models.................. 99
4.5.4 Data acquisition...................103
4.5.5 fMRI analysis.....................104
4.5.6 EEG preprocessing, analysis, source localization . 106
4.6 Acknowledgments.......................107
4.7 Conflict of interest......................107
4.8 Supplementary materials...................107
5 Study D 111
5.1 Abstract............................111
5.2 Introduction..........................112
5.3 Material and methods....................113
5.3.1 Subjects........................113
5.3.2 Task..........................115
5.3.3 Reinforcement learning model............115
5.3.4 Data acquisition...................116
5.3.5 fMRI data analysis..................116
5.3.6 EEG data analysis..................117
5.3.7 fMRI-informed EEG data analysis.........117
5.4 Results.............................118
5.4.1 fMRI main effects ..................118
5.4.2 Temporal localization of the ROIs .........118
5.5 Discussion...........................119
5.6 Conclusions..........................121
6 General Discussion 123
6.1 Simultaneous EEG-fMRI in (mal-)adaptive learning and
decision making - what have we learned and what to come? 123
6.2 Imaging of (mal-) adaptive learning and decision making
- a helpful path for psychiatry?...............126
6.3 Conclusions..........................128
Abbreviations 130
References 132
Acknowledgments 161
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| indexdate | 2024-12-20T16:58:29Z |
| institution | BVB |
| language | English German |
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| spellingShingle | Hauser, Tobias U. 1984- Reward prediction errors in the brain methodological, developmental and psychiatric aspects of (mal-)adaptive learning and decision making Psychische Störung (DE-588)4047686-8 gnd Antizipation (DE-588)4002342-4 gnd Fehleinschätzung (DE-588)4817534-1 gnd Kognitive Störung (DE-588)4164473-6 gnd Positive Verstärkung (DE-588)4130205-9 gnd |
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| title | Reward prediction errors in the brain methodological, developmental and psychiatric aspects of (mal-)adaptive learning and decision making |
| title_auth | Reward prediction errors in the brain methodological, developmental and psychiatric aspects of (mal-)adaptive learning and decision making |
| title_exact_search | Reward prediction errors in the brain methodological, developmental and psychiatric aspects of (mal-)adaptive learning and decision making |
| title_full | Reward prediction errors in the brain methodological, developmental and psychiatric aspects of (mal-)adaptive learning and decision making by Tobias U. Hauser |
| title_fullStr | Reward prediction errors in the brain methodological, developmental and psychiatric aspects of (mal-)adaptive learning and decision making by Tobias U. Hauser |
| title_full_unstemmed | Reward prediction errors in the brain methodological, developmental and psychiatric aspects of (mal-)adaptive learning and decision making by Tobias U. Hauser |
| title_short | Reward prediction errors in the brain |
| title_sort | reward prediction errors in the brain methodological developmental and psychiatric aspects of mal adaptive learning and decision making |
| title_sub | methodological, developmental and psychiatric aspects of (mal-)adaptive learning and decision making |
| topic | Psychische Störung (DE-588)4047686-8 gnd Antizipation (DE-588)4002342-4 gnd Fehleinschätzung (DE-588)4817534-1 gnd Kognitive Störung (DE-588)4164473-6 gnd Positive Verstärkung (DE-588)4130205-9 gnd |
| topic_facet | Psychische Störung Antizipation Fehleinschätzung Kognitive Störung Positive Verstärkung Hochschulschrift |
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